Jonah Nadelmann Keller is an M.D. candidate and Twenty-First Century Scholar at the Perelman School of Medicine at the University of Pennsylvania, studying the intersection of neuroscience, artificial intelligence, and global health. He graduated from Cornell University in three years with a B.A. in Computational Biology, serving as College Degree Marshal as one of the top two most academically distinguished students in his class and earning election to Phi Beta Kappa.

At the Icahn School of Medicine at Mount Sinai, he developed novel machine learning approaches under Dr. Fanny Elahi to understand neurovascular contributions to brain aging and neurodegeneration. His research identified the plasma proteomic signature of a rare vascular dementia syndrome (CADASIL) and investigated how inflammatory processes drive neurodegeneration through vascular and immune dysfunction. He has presented findings at international conferences and has manuscripts under review at leading journals including Nature Aging, Nature: Neuroscience, Cell, and Science Advances.

His global health work spans from indigenous Kichwa communities in the Ecuadorian Amazon—studying the integration of ancestral and Western medicine—to Mongolia with the Virtue Foundation’s neurosurgery team expanding access to epilepsy surgery. These foundational experiences revealed to him that effective neurological care requires not only providing treatment but understanding patients within their complete context: their access to care, support systems, and approach to healing.

As a physician, he aims to expand global neurological care by developing AI-driven tools that leverage data science while still honoring the intimate art of medicine, creating solutions that adapt treatments to optimize outcomes for each patient's specific reality.

Raised in New York City in an interfaith household—his mother the daughter of a rabbi and his father a former Jesuit priest—he learned early to appreciate difference through listening deeply, a perspective he hopes to carry each day in his life as a physician. Outside medicine, he studies Spanish, works as a mentor with the college-access organization Y Tú También, and enjoys piano, chess, and basketball.